From GUT (International Journal of Gastroenterology and Hepatology
- Therapy update
- Probiotics in inflamatory bowel disease
- F Shanahan
- Professor F Shanahan, Department of Medicine, Cork University Hospital, Cork, Ireland.FShanahan@ucc.ie
Probiotics are live micro-organisms that alter the enteric microflora and have a beneficial effect on health. Bacteria associated with probiotic activity have frequently been lactobacilli or bifidobacteria, but Escherichia coli and enterococcal strains have been used, as have non-bacterial organisms such as Saccharomyces boulardii.
The rationale for using probiotics in inflammatory bowel disease (IBD) is based on persuasive evidence implicating intestinal bacteria in the pathogenesis of IBD.
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